Graduate Institute of Basic Medical Science, China Medical University, Taiwan
Welcome to our laboratory, we are interested in the following topics:
Prediction of Metal Ion-Binding Sites in Proteins Using the Fragment Transformation Method

 

Protein functional sites detection:

 

  • Lu CH*, Yu CS, Lin YF and Chen JY. Predicting Flavin and Nicotinamide Adenine Dinucleotide Binding Sites in Proteins Using the Fragment Transformation Method. BioMed Research International (2015), Volume 2015, Article ID 402536
  • Lu CH, Chien YT, Yu CS and Huang SW*. EXIA2: Web Server of Accurate and Rapid Protein Catalytic Residue Prediction. BioMed Research International (2014), Volume 2014, Article ID 807839
  • Lu CH*, Lin YF, Lin JJ, Yu CS. Prediction of Metal Ion-Binding Sites in Proteins Using the Fragment Transformation Method. PLoS One (2012), 7(6):e39252
  • Lu CH, Lin YS, Chen YC, Yu CS, Chang SY, Hwang JK*. The fragment transformation method to detect the protein structural motifs. Proteins: Sturcture, Function and Bioinformatics (2006), 63:636-43

 

 
CELLO2GO: A Web Server for Protein subCELlular LOcalization Prediction with Functional Gene Ontology Annotation

 

Protein subcellular localization:

 

  • Yu CS, Cheng CW, Chang KC, Su WC, Huang SW, Hwang JK and Lu CH*. CELLO2GO: A Web Server for Protein subCELlular LOcalization Prediction with Functional Gene Ontology Annotation. PLoS One (2014), 9(6):e99368
  • Yu CS, Chen YC, Lu CH, Hwang JK*. Prediction of protein subcellular localization. Proteins: Sturcture, Function and Bioinformatics (2006), 64: 643-51

 

 
On the relationship between the protein structure and protein dynamics

 

Protein dynamics:

 

  • Lu CH, Huang SW, Lai YL, Lin CP, Shih CH, Huang CC, Hsu WL and Hwang JK*. On the relationship between the protein structure and protein dynamics. Proteins: Structure, Function and Bioinformatics (2008), 72: 625-34
  • Lin CP, Huang SW, Lai YL, Yen SC, Shih CH, Lu CH, Huang CC and Hwang JK*. Deriving protein dynamical properties from weighted protein contact number. Proteins: Structure, Function and Bioinformatics (2008), 72: 929-35

 

 
Predicting disulfide connectivity patterns

 

Others:

 

  • Liu GT, Hwang CS, Hsieh CH, Lu CH, Chang LY, Lee JC, Huang CF, and Chang CH*. Eosinophil-Derived Neurotoxin is elevated in Patients with Amyotrophic Lateral Sclerosis. MEDIATORS OF INFLAMMATION, (2013) Article ID 421389
  • Yu CS* and Lu CH. Identification of Antifreeze Proteins and Their Functional Residues by Support Vector Machine and Genetic Algorithms based on n-Peptide Compositions. PLoS One (2011), 6(5):e20445
  • Lu CH, Chen YC, Yu CS, Hwang JK*. Predicting disulfide connectivity patterns. Proteins: Structure, Function and Bioinformatics (2007), 67: 262-70